1-Ethynyl-2-fluorobenzene

CAS NO.：766-49-4
Empirical Formula: C8H5F
Molecular Weight: 120.12
MDL number: MFCD00799540
SAFETY DATA SHEET (SDS)
Update Date: 2026-09-12 18:48:06

What is 1-Ethynyl-2-fluorobenzene?

Chemical properties

clear yellow to brownish liquid

The Uses of 1-Ethynyl-2-fluorobenzene

Employed in studies on the polymerization1 and cross-coupling2 of phenylacetylenes.

The Uses of 1-Ethynyl-2-fluorobenzene

1-Ethynyl-2-fluorobenzene has been employed in the cross-coupling of phenylacetylenes. It may be used in the preparation of 3-(2-deoxy-β-D-ribofuranosyl)-6-(2-fluorophenyl)-2,3-dihydrofuro-[2,3-d]pyrimidin-2-one and 4-(2-fluorophenylethynyl)-3-methyl-5-phenylisoxazole.

What are the applications of Application

1-Ethynyl-2-fluorobenzene is used to study polymerization and cross-coupling of phenylacetylenes

What are the applications of Application

General Description

1-Ethynyl-2-fluorobenzene, a fluorinated benzene derivative, is a terminal alkyne.

Properties of 1-Ethynyl-2-fluorobenzene

Boiling point:	150 °C (lit.)
Density	1.06 g/mL at 25 °C (lit.)
refractive index	1.524-1.527
Flash point:	37 °C
storage temp.	2-8°C
form	Liquid
color	Clear yellow to brownish
CAS DataBase Reference	766-49-4(CAS DataBase Reference)

Safety information for 1-Ethynyl-2-fluorobenzene

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.