1-Cyanotetraline
- CAS NO.：56536-96-0
- Empirical Formula: C11H11N
- Molecular Weight: 157.21
- MDL number: MFCD08703294
- EINECS: 611-399-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-14 15:27:00
What is 1-Cyanotetraline?
Chemical properties
light yellow oil liquid
The Uses of 1-Cyanotetraline
1-Cyanotetraline is used in the synthesis of aldose reductase inhibitors. Also reductase enzymes are believed to catalyze the formation of sorbitol from glucose leading to the chronic complications of diabetes mellitus. It is also used in the synthesis of baclofen analogs, potent GABAB agonists.
The Uses of 1-Cyanotetraline
1-Cyanotetraline is used in the synthesis of aldose reductase inhibitors. Also reductase enzymes are believed to catalyze the formation of sorbitol from glucose leading to the chronic complications of diabetes mellitus. It is also used in the synthesis of baclofen analogs, potent GABAB agonists.
Synthesis Reference(s)
Journal of the American Chemical Society, 99, p. 959, 1977 DOI: 10.1021/ja00445a057
Tetrahedron Letters, 36, p. 4307, 1995 DOI: 10.1016/0040-4039(95)00746-Y
Properties of 1-Cyanotetraline
| Melting point: | 48-50 °C |
| Boiling point: | 309 °C |
| Density | 1.06 |
| refractive index | 1.55 |
| Flash point: | 114 °C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Sparingly), DMSO (Slightly), Ethyl Acetate (Slightly) |
| form | Oil |
| color | Colourless to Yellow |
Safety information for 1-Cyanotetraline
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 1-Cyanotetraline
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