1-Boc-Pyrrolidine
Synonym(s):tert-Butyl 1-pyrrolidinecarboxylate
- CAS NO.：86953-79-9
- Empirical Formula: C9H17NO2
- Molecular Weight: 171.24
- MDL number: MFCD00216581
- EINECS: 617-940-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:26:22
What is 1-Boc-Pyrrolidine?
Chemical properties
liquid
The Uses of 1-Boc-Pyrrolidine
1-Boc-pyrrolidine is a boc-protected cyclic amine used as a building block in the preparation of diastereomers by usually undergoing α'-lithiations and electrophilic substitution reactions.
The Uses of 1-Boc-Pyrrolidine
N-Boc-pyrrolidine may be used in the synthesis of the following:
- 2-aryl-N-boc-pyrrolidines
- scalemic 2-pyrrolidinylcuprates
- 2-alkenyl-N-Boc-pyrrolidines
- 1-deoxycastanospermine
- methylphenidate analogues
- (+)-elaeokanine A
General Description
N-Boc-pyrrolidine is an N-substituted pyrrolidine. It is reported that the reactivity of N-Boc-pyrrolidine towards C-H insertion reaction is 2000 times more than cyclohexane. It undergoes α-arylation in the presence of a palladium catalyst with high enantioselectivity.
Properties of 1-Boc-Pyrrolidine
| Boiling point: | 80 °C/0.2 mmHg (lit.) |
| Density | 0.977 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 187 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform, Methanol |
| form | Oil |
| pka | -1.28±0.20(Predicted) |
| color | Clear Colorless |
| BRN | 4664750 |
| CAS DataBase Reference | 86953-79-9(CAS DataBase Reference) |
Safety information for 1-Boc-Pyrrolidine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-Boc-Pyrrolidine
New Products
Mirtazapine Impurity C/Mirtazapine Lactam Impurity Tetrabutylammonium perchlorate DL-beta-(3-Bromophenyl)alanine N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid (R)-1-Benzyl-3-pyrrolidinecarbonitrile N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 2,2'-(5-methyl-1,3-phenylene)-di(2-Methylpropionitrile) 1-methyl amino-2,4-dinitro benzene 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy Benzylcyanide valeronitrile 4-Bromo BenzylcyanideRelated products of tetrahydrofuran
You may like
-
86953-79-9 N-(tert-Butoxycarbonyl)pyrrolidine 98%View Details
86953-79-9 -
1-tert-Butoxycarbonylpyrrolidine CAS 86953-79-9View Details
86953-79-9 -
N-Boc-pyrrolidine CAS 86953-79-9View Details
86953-79-9 -
Clidinium Bromide Impurity NLT 95%View Details
.6581-06-2 -
192110-67-2 NLT 95%View Details
192110-67-2 -
Cetirizine EP Impurity A/Cetirizine CBHP Impurity NLT 95%View Details
59872-62-1 -
.2005-04-1 N-Nitroso hydroxy Cetrizine EP Impurity-A NLT 95%View Details
.2005-04-1 -
145773-22-1 Lantanoprost rc B NLT 95%View Details
145773-22-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.