1-Adamantaneacetic acid
Synonym(s):1-Adamantylacetic acid
- CAS NO.：4942-47-6
- Empirical Formula: C12H18O2
- Molecular Weight: 194.27
- MDL number: MFCD00074728
- EINECS: 225-585-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-11 17:37:59
What is 1-Adamantaneacetic acid?
Chemical properties
white to off-white crystalline powder or crystals
The Uses of 1-Adamantaneacetic acid
1-Adamantaneacetic acid was used as an acylating agent in determining pharmacological characteristics of ten new analogues of bradykinin (Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg) that were modified in the N-terminal part of the molecule.
What are the applications of Application
1-Adamantaneacetic acid is an acylating agent
Biochem/physiol Actions
1-Adamantaneacetic acid is an inhibitor of chorismate mutase-prephenate dehydrogenase (EC 1.3.1.12) from Escherichia coli K12 (strain JP 232).
Purification Methods
Dissolve the acid in hot NaOH, treat with charcoal, filter and acidify. Collect the solid, wash it with H2O, dry and recrystallise it from MeOH. [Stetter et al. Chem Ber 92 1629 1959.] The acid chloride [2094-72-6] has M 168.7, m 51-54o, and b 135-136o/1mm. LACHRYMATORY.
Properties of 1-Adamantaneacetic acid
| Melting point: | 134-137 °C (lit.) |
| Boiling point: | 270.73°C (rough estimate) |
| Density | 1.0086 (rough estimate) |
| refractive index | 1.4949 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Solubility in Methanol - almost transparency |
| form | Crystalline Powder or Crystals |
| pka | 5.00±0.10(Predicted) |
| color | White to off-white |
| BRN | 641412 |
| CAS DataBase Reference | 4942-47-6(CAS DataBase Reference) |
| NIST Chemistry Reference | 1-Adamantaneacetic acid(4942-47-6) |
Safety information for 1-Adamantaneacetic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 1-Adamantaneacetic acid
| InChIKey | AOTQGWFNFTVXNQ-UHFFFAOYSA-N |
New Products
Boc-N-Me-Val-OH tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Indole Methyl Resin Gabapentin EP Impurity B Ethyl N-(2- cyanoacetyl)carbamate Magnessium Ascorbate 1-Chloro-4-Methyl-2-Nitrobenzene 1,3-Diethyl-1,3-Diphenylurea 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile Methyl 2-methylquinoline-6-carboxylate 2,4-dihydroxybenzaldehyde 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile Benzethonium Chloride Trenbolone Enanthate Prednisolone acetate Cisplatin Chlorodehydromethyl testosterone Ketoconazole 1,3-Di Iodo Benzene Methyl 2-oxo-2,3-dihydrobenzo[d]oxazole-7-carboxylate 3-Hydroxy-4-nitrobromobenzene 4-(2-Aminoethyl)-7-hydroxy-2H-chromoen-2-one 2-Ethyl-1,4-diaminobenzene 2-Ethylhexyl 4-aminobenzoateRelated products of tetrahydrofuran
You may like
-
1-Adamantaneacetic acid CAS 4942-47-6View Details
4942-47-6 -
1-Adamantaneacetic Acid CAS 4942-47-6View Details
4942-47-6 -
1-Adamantaneacetic acid CAS 4942-47-6View Details
4942-47-6 -
tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate 98%View Details
2640989-54-2 -
Indole Ethyl Resin 98%View Details
-
Indole Methyl Resin 98%View Details
-
N,N-Dicyclohexylcarbodiimide(DCC) 99%View Details
538-75-0 -
2-Methoxyphenothiazine >98%View Details
1771-18-2
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.