1-(4-METHYLBENZYL)PIPERAZINE
- CAS NO.：23173-57-1
- Empirical Formula: C12H18N2
- Molecular Weight: 190.28
- MDL number: MFCD01075235
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:28
What is 1-(4-METHYLBENZYL)PIPERAZINE?
The Uses of 1-(4-METHYLBENZYL)PIPERAZINE
is a useful synthetic intermediate in the synthesis of 3-Desmethyl 4-Methyl Meclizine Dihydrochloride ; a metabolite of Meclizine (, 2HCl monohydrate) which is an antiemetic. 1-(4-Methylbenzyl)piperazine is also used in the synthesis of inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase
Properties of 1-(4-METHYLBENZYL)PIPERAZINE
| Melting point: | 37-41 °C(lit.) |
| Boiling point: | 115-117°C 1mm |
| Density | 1.011±0.06 g/cm3(Predicted) |
| Flash point: | 205 °F |
| pka | 9.16±0.10(Predicted) |
| CAS DataBase Reference | 23173-57-1 |
Safety information for 1-(4-METHYLBENZYL)PIPERAZINE
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 1-(4-METHYLBENZYL)PIPERAZINE
| InChIKey | RNAXUUAJNMDESG-UHFFFAOYSA-N |
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline (4-Bromophenyl)(3-methoxyphenyl)methanone 4,5,7-Trimethyl-2(1H)-quinolinone 4-(6-HYDROXYHEXYLOXY)BENZOIC ACID 4-Hydroxy-6-methyl-1-(4-methylphenyl)-2naphthalenecarboxylic acid 2,6-Piperidinedione, 3-hydroxy-1-[(4-methoxyphenyl)methyl]- NA Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 4 - fluoro- 2 - methoxy- 5 - nitroaniline 1-(2-amino-5-hydroxy phenyl)propan-1-one tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 5-bromo-2-chloro-N- cyclopentylpyrimidin-4- amine 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3-chlorobenzyl cyanide 3,4 Dimethoxy BenzylcyanideRelated products of tetrahydrofuran
![ETHYL 2-[1-(4-METHYLBENZOYL)-3-OXO-2-PIPERAZINYL]ACETATE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB2102759.gif)
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