1-(4-Isobutylphenyl)ethanol

CAS NO.：40150-92-3
Empirical Formula: C12H18O
Molecular Weight: 178.27
MDL number: MFCD08275597
EINECS: 641-487-5
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:26:16

What is 1-(4-Isobutylphenyl)ethanol?

The Uses of 1-(4-Isobutylphenyl)ethanol

1-(4-Isobutylphenyl)ethanol is a photodegradation product of Ibuprofen (I140000). Shows cytotoxicity activity.

What are the applications of Application

1-(4-Isobutylphenyl)ethanol is a photodegradation product of Ibuprofen

Preparation

1-(4-Isobutylphenyl)ethanol synthesis: A solution of p-isobutylacetophenone (1.20mL), methanol (3.00mL), and sodium borohydride (0.2509g) was mixed in a separatory funnel and allowed to sit for 10min. After the standing time period, a 10 % HCl solution (10.0 mL) was added to remove any unreacted sodium borohydride, and the product was extracted using petroleum ether. 1-(4-Isobutylphenyl)ethanol product (1.002g, 87.2%) was collected and dried using anhydrous sodium sulfate.
1HNMR (300MHz, CDCl3): δ7.281 (2H, m, J = 4.0 Hz), δ7.174 (2H, m, J = 4.0 Hz), δ4.855 (1H, s, J =0.92Hz), δ2.714 (3H, q, J =2.2Hz), δ2.554 (2H, t, J = 2.8 Hz), δ1.795 (1H, q, J = 2.7 Hz), δ1.484 (1H, m, J =2.8Hz), δ0.976 (6H, q, J =6.1Hz). 13C NMR (300 MHz, CDCl3): 143.325, 140.684, 129.143, 125.357, 70.034, 45.196, 30.343, 25.076, 22.725, 22.465.

Properties of 1-(4-Isobutylphenyl)ethanol

Boiling point:	111 °C(Press: 1 Torr)
Density	0.954±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Oil
pka	14.53±0.20(Predicted)
color	Colourless
EPA Substance Registry System	Benzenemethanol, .alpha.-methyl-4-(2-methylpropyl)- (40150-92-3)