1-(2,6-Difluorophenyl)ethan-1-one
- CAS NO.:13670-99-0
- Empirical Formula: C8H6F2O
- Molecular Weight: 156.13
- MDL number: MFCD00000328
- EINECS: 237-151-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:59:02
What is 1-(2,6-Difluorophenyl)ethan-1-one?
Chemical properties
Clear colourless to light yellow liquid
The Uses of 1-(2,6-Difluorophenyl)ethan-1-one
2?,6?-Difluoroacetophenone was used in the synthesis of 2-amino-4-alkyl- and 2-amino-4-arylquinazolines.
General Description
2′,6′-Difluoroacetophenone undergoes ruthenium-catalyzed phenylation with phenylboronate via carbon-fluorine bond cleavage to yield 2′,6′-diphenylacetophenone.
Properties of 1-(2,6-Difluorophenyl)ethan-1-one
| Melting point: | 52-55°C |
| Boiling point: | 76-79 °C15 mm Hg(lit.) |
| Density | 1.197 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 170 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Liquid |
| color | Clear colorless to slightly yellow |
| Specific Gravity | 1.197 |
| Water Solubility | Slightly soluble in water. |
| BRN | 2046068 |
| CAS DataBase Reference | 13670-99-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethanone, 1-(2,6-difluorophenyl)-(13670-99-0) |
Safety information for 1-(2,6-Difluorophenyl)ethan-1-one
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-(2,6-Difluorophenyl)ethan-1-one
New Products
2-Ethoxyphenol Methyl 2-methoxy-5-sulfamoylbenzoate Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 3,6-Dichloropyridazine 3,6-Dichloro-4-Isopropylpyridazine 2-[(2-Ethoxyphenoxy)methyl]oxirane m-Tolualdehyde p-Anisaldehyde 2-Bromobenzaldehyde 4-Fluorobenzaldehyde 1-Propyl-4-piperidone 3-Amino-3-(3-fluorophenyl)propanoic acid 6-Methyl-2-pyridinemethanol 2-Pyridinecarboxaldehdye tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate 1-Indanone 2-Chloromethyl-6-methyl-pyridine 4-Morpholinoaniline Abiraterone Ethyl Ether 1-nitro-3,5-dimethyl adamantine (NMEM) Vardenafil Bis-sulphonamide(Dimer) 3-(2-aminoethyl) benzene sulfonamide Nabumetone Impurity 5 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-oneRelated products of tetrahydrofuran



![2,2,2-TRICHLORO-1-[4-(2,6-DIFLUOROBENZOYL)-1H-PYRROL-2-YL]-1-ETHANONE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB2465962.gif)




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