1-(2-hydroxyphenyl)-2-phenylethanone

CAS NO.：2491-31-8
Empirical Formula: C14H12O2
Molecular Weight: 212.24
MDL number: MFCD00218589
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 02:44:57

What is 1-(2-hydroxyphenyl)-2-phenylethanone?

Preparation

Obtained by Fries rearrangement of phenyl phenylacetate,Also obtained by photo-Fries rearrangement of phenyl phenylacetate, ? in the presence of a- or b-cyclodextrin in organic solvents ; ? included in a Nafion membrane, at r.t. for 7 h (quantitative yield).? with aluminium chloride,
with titanium tetrachloride in chlorobenzene at 50° for 4 h (<5%);
? with polyphosphoric acid at 100° (1%);
? with or without 20% Bleicherde at 200° for 9 h (poor yields).

Properties of 1-(2-hydroxyphenyl)-2-phenylethanone

Melting point:	55.0 to 59.0 °C
Boiling point:	165°C/23mmHg(lit.)
Density	1.178±0.06 g/cm3(Predicted)
pka	8.09±0.30(Predicted)
form	powder to crystal
color	Light yellow to Amber to Dark green

Safety information for 1-(2-hydroxyphenyl)-2-phenylethanone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 1-(2-hydroxyphenyl)-2-phenylethanone

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