1-(2-Amino-5-hydroxyphenyl)propan-1-one
- CAS NO.：35364-15-9
- Empirical Formula: C9H11NO2
- Molecular Weight: 165.19
- MDL number: MFCD16877176
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 1-(2-Amino-5-hydroxyphenyl)propan-1-one?
The Uses of 1-(2-Amino-5-hydroxyphenyl)propan-1-one
1-(2-Amino-5-hydroxyphenyl)propan-1-one is a useful synthetic intermediate. It is used in the asymmetrical synthesis of (S)-4-ethyl-6,7,8,10- tetrahydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione, a key intermediate for synthesis of irinotecan and other camptothecin analogs. It is also used in the synthesis of E-?ring-?modified (RS)?-?camptothecin analogs as antitumor agents.
Preparation
Obtained by UV-irradiation of 3-ethyl-2,1-benzisoxazole in 66% sulfuric acid for 90 min at 80–90°
Also prepared from 2-nitro-5-hydroxybenzaldehyde (five steps) or from p-anisidine.
Properties of 1-(2-Amino-5-hydroxyphenyl)propan-1-one
| Melting point: | 144.5-144.9 °C |
| Boiling point: | 363.9±32.0 °C(Predicted) |
| Density | 1.195±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 9.35±0.18(Predicted) |
| color | Light Yellow to Brown |
| Stability: | Hygroscopic |
Safety information for 1-(2-Amino-5-hydroxyphenyl)propan-1-one
Computed Descriptors for 1-(2-Amino-5-hydroxyphenyl)propan-1-one
1-(2-Amino-5-hydroxyphenyl)propan-1-one manufacturer
OCIMUM LIFESCIENCES PVT LTD
3Y
Phone:+91-8891777669
Whatsapp: +91- 8891777669
product: 35364-15-9 97%
ALS India Life Sciences Pvt. Ltd
2Y
Phone:+91-8977036378
Whatsapp: +91 8008166674
product: 1-(2-Amino-5-hydroxyphenyl)propan-1-one 99.96%
New Products
tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Boc-His-OH 1-Chloro-4-Methyl-2-Nitrobenzene 4-Bromo-2-chlorobenzonitrile 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile 1,3-Diethyl-1,3-Diphenylurea Methyl 2-methylquinoline-6-carboxylate 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile Benzethonium Chloride Trenbolone Enanthate Prednisolone acetate Cisplatin Chlorodehydromethyl testosterone Ketoconazole 2,4-Difluoro-5-nitrobenzoicacid Methyl 2-oxo-2,3-dihydrobenzo[d]oxazole-7-carboxylate 3-Hydroxy-4-nitrobromobenzene 4-(2-Aminoethyl)-7-hydroxy-2H-chromoen-2-one 2-Ethyl-1,4-diaminobenzene 2-Ethylhexyl 4-aminobenzoate Fmoc-N-Me-Ala-OH Fmoc-N-Me-Ile-OH Indole Ethyl Resin Indole Methyl ResinYou may like
-
2'-Amino-5'-hydroxy propiophenone 99%View Details
35364-15-9 -
1-(2-Amino-5-hydroxyphenyl)propan-1-one 99.96%View Details
35364-15-9 -
35364-15-9 97%View Details
35364-15-9 -
tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate 98%View Details
2640989-54-2 -
Indole Ethyl Resin 98%View Details
-
Indole Methyl Resin 98%View Details
-
N,N-Dicyclohexylcarbodiimide(DCC) 99%View Details
538-75-0 -
2-Methoxyphenothiazine >98%View Details
1771-18-2
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.