(-)-PERILLYL ALCOHOL
Synonym(s):(S)-p-Mentha-1,8-dien-7-ol;(S)-4-Isopropenyl-1-cyclohexenylmethanol;p-Mentha-1,8-diene-7-ol
- CAS NO.：18457-55-1
- Empirical Formula: C10H16O
- Molecular Weight: 152.23
- MDL number: MFCD00062995
- EINECS: 629-611-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is (-)-PERILLYL ALCOHOL?
Description
(–)-Perillyl alcohol is a monoterpene alcohol that has been found in lavender essential oil and has diverse biological activities. It reduces production of hydroperoxidienes and thiobarbituric acid reactive substances (TBARS) in vitro in a concentration-dependent manner. (–)-Perillyl alcohol inhibits PANC-1 pancreatic carcinoma cell and H-Ras-transformed fibroblast growth when used at a concentration of 1 mM. It also inhibits the growth of P. aeruginosa, E. coli, S. aureus, and C. albicans (MICs = 480-2,900 ppm).
The Uses of (-)-PERILLYL ALCOHOL
(-)-Perillyl Alcohol is a monoterpene that induces apoptosis in colon tumor cells. Also, it is used in preparation of terpene-vanilloid conjugates as anti-inflammatory agents.
What are the applications of Application
(?)-Perillyl Alcohol is A monoterpene that induces apoptosis in colon tumor cells
Definition
ChEBI: (S)-(-)-perillyl alcohol is a perillyl alcohol in which the chiral centre has S configuration. It is an enantiomer of a (R)-(+)-perillyl alcohol.
General Description
(S)-(-)-Perillyl alcohol is a monoterpenoid compound found in the essential oils of cherries, lavender and spearmint. It shows potent anticancer activity.
Properties of (-)-PERILLYL ALCOHOL
| Boiling point: | 119-121 °C11 mm Hg(lit.) |
| alpha | -101o (NEAT) |
| Density | 0.96 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), Methanol (Sparingly) |
| form | neat |
| pka | 14.85±0.10(Predicted) |
| form | Liquid |
| Specific Gravity | 0.960 |
| color | Colourless |
| optical activity | [α]22/D 88°, c = 1 in methanol |
| BRN | 2501605 |
| CAS DataBase Reference | 18457-55-1(CAS DataBase Reference) |
Safety information for (-)-PERILLYL ALCOHOL
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (-)-PERILLYL ALCOHOL
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