(-)-MENTHYL CHLORIDE

Synonym(s):(1R)-(−)-Menthyl chloride;(1S,2R,4R)-2-Chloro-1-isopropyl-1-methylcyclohexane;[1S-(1α,2β,4β)]-2-Chloro-4-methyl-1-(methylethyl)cyclohexane

CAS NO.：16052-42-9
Empirical Formula: C10H19Cl
Molecular Weight: 174.71
MDL number: MFCD00001481
EINECS: 240-200-7
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 03:19:20

What is (-)-MENTHYL CHLORIDE?

The Uses of (-)-MENTHYL CHLORIDE

2-Chloro-4-methyl-1-(1-methylethyl)-Cyclohexane is a useful building block for organic synthesis.

Purification Methods

Dissolve menthyl chloride in pet ether (b 40-60o), wash with H2O, conc H2SO4 until no discoloration of the organic layer occurs (care with conc H2SO4 during shaking in a separating funnel), again with H2O and dry it (MgSO4). Evaporate and distil the residual oil through a Claisen head with a Vigreux neck ( p 11) of ca 40 cm length. [Smith & Wright J Org Chem 17 1116 1952, Barton et al. J Chem Soc 453 1952, Beilstein 5 III 134.]

Properties of (-)-MENTHYL CHLORIDE

Melting point:	−20-−16.5 °C(lit.)
Boiling point:	101-101.5 °C21 mm Hg(lit.)
Density	0.936 g/mL at 25 °C(lit.)
refractive index	n20/D 1.464
Flash point:	174 °F
form	clear liquid
color	Colorless to Light yellow
optical activity	[α]20/D 52.4°, neat
BRN	1902297

Safety information for (-)-MENTHYL CHLORIDE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H227:Flammable liquids H302:Acute toxicity,oral
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use … for extinction. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..…