(-)-GUAIOL
Synonym(s):(3R,6S,10S)-6,10,α,α-Tetramethylbicyclo[5.3.0]dec-1(7)-ene-3-methanol
- CAS NO.：489-86-1
- Empirical Formula: C15H26O
- Molecular Weight: 222.37
- MDL number: MFCD00043336
- EINECS: 207-702-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:17
What is (-)-GUAIOL?
Chemical properties
Crystalline solid. Insoluble in water; soluble in alcohol.
The Uses of (-)-GUAIOL
Guaiol is a component of guaiac wood oil, terpenol also found in cannabis.
Definition
A bicyclic sesquiterpene alcohol found in guaiac wood oil.
Production Methods
(-)-Guaiol can be produced by extraction from Guaiacwood oil
with a volatile solvent, usually Acetone,
Ethanol or Ethylether.
It can also be isolated from the wood of
certain Australian members of the family
Taxodiaceae, particularly the so-called "Murray River Pine".
General Description
(-)-Guaiol is a sesquiterpene alcohol which has guaiane skeleton. It naturally occurs in essential oils extracted from Salvia lanigera and Helitta ongifoliata and has antibacterial activity.
Properties of (-)-GUAIOL
| Melting point: | 91-93 °C(lit.) |
| Boiling point: | 132-136℃ |
| alpha | D20 -30° (c = 4 in alc) |
| Density | 0.9714 g/cm3 (20℃) |
| refractive index | 1.5100 (589.3 nm 20℃) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Dichloromethane (Sparingly), Ethanol (Slightly), Methanol |
| form | Solid |
| pka | 15.11±0.29(Predicted) |
| color | White to Off-White |
| Odor | at 100.00 %. mild guaiacwood tea rose |
| optical activity | [α]20/D 28°, c = 4 in ethanol |
| Merck | 13,4572 |
| BRN | 2047993 |
| EPA Substance Registry System | 5-Azulenemethanol, 1,2,3,4,5,6,7,8-octahydro-.alpha.,.alpha.,3,8-tetramethyl-, (3S,5R,8S)- (489-86-1) |
Safety information for (-)-GUAIOL
Computed Descriptors for (-)-GUAIOL
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