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Home Product name list(+/-)5-HEPE

(+/-)5-HEPE

CAS NO.：83952-40-3
Empirical Formula: C20H30O3
Molecular Weight: 318.45
MDL number: MFCD00171437
SAFETY DATA SHEET (SDS)
Update Date: 2025-04-17 18:22:24

(+/-)5-HEPE Structural

What is (+/-)5-HEPE?

Description

(±)5-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 5(S)-HEPE and 5(R)-HEPE. The biological activity of (±)5-HEPE is likely mediated by one of the individual isomers, most commonly the 5(S) isomer in mammalian systems. EPA can be metabolized to 5-HEPE in human and bovine neutrophils, and human eosinophils, which is further metabolized to 5-oxoEPE and LTB₅. The 5-series metabolites of EPA, namely 5-HEPE, 5-oxoEPE, and LTB₅, have significantly decreased biological effects compared to the arachidonic acid-derived metabolites.

What are the applications of Application

(±)5-HEPE is a compound produced by non-enzymatic oxidation of EPA

Definition

ChEBI: 5-HEPE is a hydroxyicosapentaenoic acid that consists of 6E,8Z,11Z,14Z,17Z-icosapentaenoic acid with the hydroxy group located at position 5. It has a role as a mouse metabolite. It is a conjugate acid of a 5-HEPE(1-).

Properties of (+/-)5-HEPE

Boiling point:	488.0±45.0 °C(Predicted)
Density	0.997±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
form	Clear to light-yellow liquid.
pka	4.67±0.10(Predicted)

Safety information for (+/-)5-HEPE

Computed Descriptors for (+/-)5-HEPE

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Related products of tetrahydrofuran

dendrotoxin K

(±)-5-HETE, (±)-(6E,8Z,11Z,14Z)-5-Hydroxyeicosatetraenoic acid solution

(±)-5-HETE, (±)-(6E,8Z,11Z,14Z)-5-Hydroxyeicosatetraenoic acid solution

(+/-)5-HEPE

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