COMPUTED DESCRIPTORS
| Molecular Weight | 525.8 g/mol |
|---|---|
| XLogP3 | 9.1 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 14 |
| Exact Mass | 525.41819462 g/mol |
| Monoisotopic Mass | 525.41819462 g/mol |
| Topological Polar Surface Area | 60.8 Ų |
| Heavy Atom Count | 38 |
| Formal Charge | 0 |
| Complexity | 727 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 6 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
ICI-164384 is a 3-hydroxy steroid that is 17beta-estradiol substituted by a 11-[butyl(methyl)amino]-11-oxoundecyl group at position 7R. It is a steroidal antioestrogen that inhibits the cell proliferation of breast-carcinoma cell lines. It has a role as an estrogen receptor antagonist, an anti-estrogen and an antineoplastic agent. It is a 3-hydroxy steroid, a 17beta-hydroxy steroid and a tertiary carboxamide. It is functionally related to a 17beta-estradiol.