92-13-7
Product Name:
PILOCARPINE
Formula:
C11H16N2O2
Synonyms:
cis-3-Ethyl-4-(1-methyl-5-imidazolylmethyl)dihydro-2(3H)-furanone
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Color/Form | OIL OR CRYSTALS |
| Boiling Point | 260 °C @ 5 MM HG (PARTIAL CONVERSION TO ISOPILOCARPINE) |
| Melting Point | 204-205 °C |
| Solubility | 1000000 mg/L (at 25 °C) |
| LogP | 1.1 |
| Stability/Shelf Life | HYGROSCOPIC. /HCL/ |
| Optical Rotation | SPECIFIC OPTICAL ROTATION: +106 DEG @ 18 °C/D (2%) |
| Decomposition | ON HEATING TO DECOMP, EMITS TOXIC FUMES OF NO(X). |
| Dissociation Constants | 6.78 |
| Other Experimental Properties | WHITE CRYSTALS; SLIGHTLY BITTER; MP: 195-198 °C; ALSO GIVEN AS 204-205 °C; 1 G DISSOLVES IN 0.3 ML WATER, 3 ML ALCOHOL, 366 ML CHLOROFORM; INSOL IN ETHER; /HCL/ |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P284:Wear respiratory protection. P310:Immediately call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
COMPUTED DESCRIPTORS
| Molecular Weight | 208.26 g/mol |
|---|---|
| XLogP3 | 1.1 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 3 |
| Exact Mass | 208.121177757 g/mol |
| Monoisotopic Mass | 208.121177757 g/mol |
| Topological Polar Surface Area | 44.1 Ų |
| Heavy Atom Count | 15 |
| Formal Charge | 0 |
| Complexity | 245 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
(+)-pilocarpine is the (+)-enantiomer of pilocarpine. It has a role as an antiglaucoma drug. It is an enantiomer of a (-)-pilocarpine.