83905-01-5

Product Name: Azithromycin

Formula: C38H72N2O12

Synonyms: N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A;Azithromycin;Azithromycin dihydrate;CP 62,993;CP-62993

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CHEMICAL AND PHYSICAL PROPERTIES SAFETY INFORMATION COMPUTED DESCRIPTORS PRODUCT INTRODUCTION RELATED SUPPLIERS

CHEMICAL AND PHYSICAL PROPERTIES

Physical Description	Solid
Color/Form	Amorphous solid
Melting Point	126
Solubility	soluble in ethanol and DSMO, minimally soluble in water
LogP	3.03
Optical Rotation	Specific optical rotation: -37 °C at 20 °C/D (c = 1 on CHCl3)
Ionization Efficiency	Positive
Dissociation Constants	8.5
Collision Cross Section	263.5 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

SAFETY INFORMATION

Signal word	Danger
Pictogram(s)	Health Hazard GHS08
GHS Hazard Statements	H317:Sensitisation, Skin H334:Sensitisation, respiratory
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P342+P311:IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

COMPUTED DESCRIPTORS

Molecular Weight	749.0 g/mol
XLogP3	4
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	14
Rotatable Bond Count	7
Exact Mass	748.50852574 g/mol
Monoisotopic Mass	748.50852574 g/mol
Topological Polar Surface Area	180 Å²
Heavy Atom Count	52
Formal Charge	0
Complexity	1150
Isotope Atom Count	0
Defined Atom Stereocenter Count	18
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

PRODUCT INTRODUCTION

description

Azithromycin is a macrolide antibiotic useful for the treatment of bacterial infections. It has a role as an antibacterial drug, an environmental contaminant and a xenobiotic.