CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Boiling Point | 688 |
| Melting Point | 240 |
| Solubility | In water, 92 mg/L at 25 °C /Estimated/ |
| Vapor Pressure | 4.56X10-13 mm Hg at 25 °C /Estimated/ |
| LogP | 1.604 |
| Henry's Law Constant | Henry's Law constant = 9.5X10-20 atm-cu m/mol at 25 °C /Estimated/ |
| Dissociation Constants | 8.13 |
| Collision Cross Section | 194.6 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)] |
| Other Experimental Properties | White to off-white crystalline powder that melts at approximately 240 °C. It is freely soluble in water, sparingly soluble in alcohol, and practically insoluble in dichloromethane. /Hydrochloride/ |
COMPUTED DESCRIPTORS
| Molecular Weight | 389.4 g/mol |
|---|---|
| XLogP3 | 1.7 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 8 |
| Exact Mass | 389.20630436 g/mol |
| Monoisotopic Mass | 389.20630436 g/mol |
| Topological Polar Surface Area | 112 Ų |
| Heavy Atom Count | 28 |
| Formal Charge | 0 |
| Complexity | 511 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Alfuzosin is a monocarboxylic acid amide, a tetrahydrofuranol and a member of quinazolines. It has a role as an antineoplastic agent, an antihypertensive agent and an alpha-adrenergic antagonist.