CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | Gray, translucent, viscous liquid |
|---|---|
| Solubility | Insoluble in water |
| Density | 0.98 /Polydimethyl Silicones/ |
| Stability/Shelf Life | Stable under recommended storage conditions. |
| Viscosity | 60,000 centistokes |
| Refractive Index | Index of refraction: 1.4040 at 20 °C |
| Other Experimental Properties | Average number of dimethylsiloxane units is 200 to 250. mol wt 14000-21000. Gray, translucent, viscous liquid. Insoluble in water, alcohol. |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
| Molecular Weight | 238.46 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 238.05128865 g/mol |
| Monoisotopic Mass | 238.05128865 g/mol |
| Topological Polar Surface Area | 52.6 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 125 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in use since the 1940s but was granted FDA approval in 1952.