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8049-62-5

Product Name: INSULIN, ZINC, BOVINE
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COMPUTED DESCRIPTORS

Molecular Weight 5873 g/mol
Hydrogen Bond Donor Count 76
Hydrogen Bond Acceptor Count 89
Rotatable Bond Count 179
Exact Mass 5869.573502 g/mol
Monoisotopic Mass 5867.566792 g/mol
Topological Polar Surface Area 2440 Ų
Heavy Atom Count 406
Formal Charge 0
Complexity 14800
Isotope Atom Count 0
Defined Atom Stereocenter Count 51
Undefined Atom Stereocenter Count 3
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Insulin, Lente is a long-acting crystalline insulin often used in combination with a short-acting insulin in the treatment of diabetes mellitus. This type of insulin may be derived from porcine or recombinant sources. Administered once daily, insulin Lente starts to lower blood glucose within 1 to 3 hours after injection and exerts its peak effect 7 to 15 hours after injection. Endogenous human insulin, a pancreatic hormone composed of two polypeptide chains, is important for the normal metabolism of carbohydrates, proteins and fats; it has anabolic effects on many types of tissues. (NCI04)