8001-27-2
Product Name:
HIRUDIN
Formula:
C287H440N80O113S7
Synonyms:
Hirudin, Hirudo medicinalis, Recombinant, Saccharomyces cerevisiae - CAS 8001-27-2 - Calbiochem
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SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H317:Sensitisation, Skin H334:Sensitisation, respiratory |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
COMPUTED DESCRIPTORS
| Molecular Weight | 7044 g/mol |
|---|---|
| XLogP3 | -40.7 |
| Hydrogen Bond Donor Count | 99 |
| Hydrogen Bond Acceptor Count | 124 |
| Rotatable Bond Count | 167 |
| Exact Mass | 7041.9288491 g/mol |
| Monoisotopic Mass | 7038.9187846 g/mol |
| Topological Polar Surface Area | 3290 Ų |
| Heavy Atom Count | 487 |
| Formal Charge | 0 |
| Complexity | 18900 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 62 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Single-chain polypeptides of about 65 amino acids (7 kDa) from LEECHES that have a neutral hydrophobic N terminus, an acidic hydrophilic C terminus, and a compact, hydrophobic core region. Recombinant hirudins lack tyr-63 sulfation and are referred to as 'desulfato-hirudins'. They form a stable non-covalent complex with ALPHA-THROMBIN, thereby abolishing its ability to cleave FIBRINOGEN.