76-42-6
Product Name:
OXYCODONE
Formula:
C18H21NO4
Synonyms:
(5α)-4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one;14-Hydroxydihydrocodeinone;Dihydrone
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Color/Form | Rods from ethanol |
| Melting Point | 219 |
| Solubility | 166mg/mL |
| LogP | 0.7 |
| Stability/Shelf Life | Stable under recommended storage conditions. /Oxycodone hydrochloride/ |
| Decomposition | When heated to decomposition it emits toxic fumes of oxides of nitrogen. |
| Dissociation Constants | 8.53 |
| Collision Cross Section | 168.3 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)] |
| Other Experimental Properties | Exists in 2 tautomeric forms which give same salt; does not reduce ammoniacal silver or Fehling's solution |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H336:Specific target organ toxicity,single exposure; Narcotic effects H362:Reproductive toxicity, effects on or via lactation |
| Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P263:Avoid contact during pregnancy/while nursing. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P308+P313:IF exposed or concerned: Get medical advice/attention. |
COMPUTED DESCRIPTORS
| Molecular Weight | 315.4 g/mol |
|---|---|
| XLogP3 | 1.2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 1 |
| Exact Mass | 315.14705815 g/mol |
| Monoisotopic Mass | 315.14705815 g/mol |
| Topological Polar Surface Area | 59 Ų |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 553 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Oxycodone is a semisynthetic opioid of formula C18H21NO4 that is derived from thebaine. It is a moderately potent opioid analgesic, generally used for relief of moderate to severe pain. It has a role as an opioid analgesic, a mu-opioid receptor agonist and an antitussive. It is an organic heteropentacyclic compound and a semisynthetic derivative. It is functionally related to a thebaine. It is a conjugate base of an oxycodone(1+). It derives from a hydride of a morphinan.