CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid; [Merck Index] Powder; [Sigma-Aldrich MSDS] |
|---|---|
| Color/Form | Needles or plates |
| Taste | Sweet |
| Melting Point | 287 dec °C |
| Solubility | 45600 mg/L (at 25 °C) |
| Vapor Pressure | 0.00000001 [mmHg] |
| LogP | -3.32 |
| LogS | -0.53 |
| Optical Rotation | Specific optical rotation:(c=0.77 in 0.5N of NaOH): -10.9 °C at 20 °C/D; (c=0.75 to 3.77): -38.95 °C at 25 °C/D; (c=1.00-4.05 in 6.1N HCl): +13.34 °C at 25 °C/D |
| Ionization Efficiency | Negative |
| Dissociation Constants | 2.76 (at 0 °C) |
| Collision Cross Section | 131.9 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)] |
| Other Experimental Properties | Softens @ 277 °C |
| Chemical Classes | Biological Agents -> Amino Acids and Derivatives |
COMPUTED DESCRIPTORS
| Molecular Weight | 155.15 g/mol |
|---|---|
| XLogP3 | -3.2 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 155.069476538 g/mol |
| Monoisotopic Mass | 155.069476538 g/mol |
| Topological Polar Surface Area | 92 Ų |
| Heavy Atom Count | 11 |
| Formal Charge | 0 |
| Complexity | 151 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
L-histidine is the L-enantiomer of the amino acid histidine. It has a role as a nutraceutical, a micronutrient, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite, an algal metabolite and a mouse metabolite. It is a proteinogenic amino acid, a histidine and a L-alpha-amino acid. It is a conjugate base of a L-histidinium(1+). It is a conjugate acid of a L-histidinate(1-). It is an enantiomer of a D-histidine. It is a tautomer of a L-histidine zwitterion.