69655-05-6
Product Name:
Dideoxyinosine
Formula:
C10H12N4O3
Synonyms:
2′,3′-Dideoxyinosine;ddI;ddIno
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | 2',3'-dideoxyinosine appears as fluffy white solid or powder. Condenses at 347 °F and darkens at approximately 572 °F. Odorless. (NTP, 1992) |
|---|---|
| Color/Form | White solid |
| Melting Point | 347 °F (decomposes) (NTP, 1992) |
| Solubility | 10 to 50 mg/mL at 70 °F (NTP, 1992) |
| Vapor Pressure | 6.6 mm Hg @ 25 °C /Estimated/ |
| LogP | -1.24 |
| Henry's Law Constant | Henry's Law constant = 2.4X10-20 atm-cu m/mol @ 25 °C /Estimated/ |
| Stability/Shelf Life | Didanosine unbuffered pediatric powder for oral solution should be stored at 15-30 °C. Following reconstitution with water and admixture with a liquid antacid as directed, didanosine pediatric oral suspensions contain 10 mg of the drug per ml and are stable for 30 days when refrigerated at 2-8 °C. Reconstituted and admixed pediatric oral suspensions of didanosine should be stored in tightly closed, flint glass bottles with child resistant closures and refrigerated at 2-8 °C. Unused portions of reconstituted and admixed pediatric didanosine oral suspension should be discarded after 30 days. |
| Optical Rotation | (c = 1, H2O) [a]20D = -25.7 ± 2° |
| Dissociation Constants | pKa= 9.13 |
| Other Experimental Properties | Hydroxyl radical reaction rate constant = 2.3X10-10 cu cm/molec=sec @ 25 °C /Estimated/ |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H341:Germ cell mutagenicity H373:Specific target organ toxicity, repeated exposure |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P501:Dispose of contents/container to..… |
COMPUTED DESCRIPTORS
| Molecular Weight | 236.23 g/mol |
|---|---|
| XLogP3 | -1.2 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 2 |
| Exact Mass | 236.09094026 g/mol |
| Monoisotopic Mass | 236.09094026 g/mol |
| Topological Polar Surface Area | 88.7 Ų |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 348 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
2',3'-dideoxyinosine appears as fluffy white solid or powder. Condenses at 347 °F and darkens at approximately 572 °F. Odorless. (NTP, 1992)