69408-81-7
Product Name:
Amonafide
Formula:
C16H17N3O2
Synonyms:
5-Amino-2-[2-(dimethylamino)ethyl]-1H-benz[de]isoquinoline-1,3(2H)-dione;AS1413;FA 142;Nafidimide;NSC 308847
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Solubility | H <1 (mg/mL) |
|---|---|
| Stability/Shelf Life | Bulk: A sample stored at 60 °C for 30 days assayed at > 99% (HPLC). Solution: A 0.4 mg/mL solution of drug in 0.2 M acetate buffer (pH4.0) showed no decomposition after 48 hours at room temperature (HPLC). |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
| Molecular Weight | 283.32 g/mol |
|---|---|
| XLogP3 | 1.5 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 283.132076794 g/mol |
| Monoisotopic Mass | 283.132076794 g/mol |
| Topological Polar Surface Area | 66.6 Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 437 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
5-amino-2-[2-(dimethylamino)ethyl]benzo[de]isoquinoline-1,3-dione is a member of isoquinolines.