55-56-1
Product Name:
Chlorhexidine
Formula:
C22H30Cl2N10
Synonyms:
1,1′-Hexamethylenebis[5-(4-chlorophenyl)biguanide];Chlorhexidine;Chlorohexidine
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Crystals from methanol; [HSDB] |
|---|---|
| Color/Form | Crystals from methanol |
| Melting Point | 134 °C |
| Solubility | 800 mg/L (at 20 °C) |
| LogP | 0.08 |
| Stability/Shelf Life | Stable under ambient warehouse conditions to moisture and simulated sunlight. /Chlorhexidine diacetate/ |
| Dissociation Constants | 10.8 (at 25 °C) |
| Other Experimental Properties | Strong alkaline reaction |
| Chemical Classes | Other Uses -> Biocides/Disinfectants |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Corrosion Corrosives GHS05  Environment GHS09 |
| GHS Hazard Statements |
H318:Serious eye damage/eye irritation H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P391:Collect spillage. Hazardous to the aquatic environment P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P501:Dispose of contents/container to..… |
COMPUTED DESCRIPTORS
| Molecular Weight | 505.4 g/mol |
|---|---|
| XLogP3 | 0.1 |
| Hydrogen Bond Donor Count | 6 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 13 |
| Exact Mass | 504.2031964 g/mol |
| Monoisotopic Mass | 504.2031964 g/mol |
| Topological Polar Surface Area | 178 Ų |
| Heavy Atom Count | 34 |
| Formal Charge | 0 |
| Complexity | 649 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 2 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Chlorhexidine is a bisbiguanide compound with a structure consisting of two (p-chlorophenyl)guanide units linked by a hexamethylene bridge. Chlorhexidine is a disinfectant that is added to soaps, cosmetics, toothpaste, and similar products. Veterinarians use it as a topical disinfectant for animals’ wounds. It is active against Gram-positive and Gram–negative bacteria, but not viruses.