51350-19-7
Product Name:
EHNA HYDROCHLORIDE
Formula:
C14H23N5O
Synonyms:
erythro-9-(2-Hydroxy-3-nonyl)-adenine hydrochloride;erythro-9-(2-Hydroxy-3-nonyl)adenine, HCl;erythro-9-Amino-β-hexyl--α-methyl-9H-purine-9-ethanol hydrochloride;EHNA, Hydrochloride - CAS 51350-19-7 - Calbiochem
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COMPUTED DESCRIPTORS
| Molecular Weight | 277.37 g/mol |
|---|---|
| XLogP3 | 2.6 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 7 |
| Exact Mass | 277.19026037 g/mol |
| Monoisotopic Mass | 277.19026037 g/mol |
| Topological Polar Surface Area | 89.8 Ų |
| Heavy Atom Count | 20 |
| Formal Charge | 0 |
| Complexity | 291 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
(2R,3S)-EHNA is eHNA of absolute configuration 2R,3S. Selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4 mM). Also a potent inhibitor of adenosine deaminase. It has a role as an EC 3.5.4.4 (adenosine deaminase) inhibitor and an EC 3.1.4.* (phosphoric diester hydrolase) inhibitor. It is a conjugate base of a (2R,3S)-EHNA(1+). It is an enantiomer of a (2S,3R)-EHNA.