51110-01-1
Product Name:
Somatostatin
Formula:
C76H104N18O19S2
Synonyms:
Growth hormone release inhibiting factor;Somatostatin-14;Somatotropin release inhibiting factor;SRIF
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COMPUTED DESCRIPTORS
| Molecular Weight | 1637.9 g/mol |
|---|---|
| XLogP3 | -3.1 |
| Hydrogen Bond Donor Count | 22 |
| Hydrogen Bond Acceptor Count | 24 |
| Rotatable Bond Count | 26 |
| Exact Mass | 1636.71665551 g/mol |
| Monoisotopic Mass | 1636.71665551 g/mol |
| Topological Polar Surface Area | 664 Ų |
| Heavy Atom Count | 115 |
| Formal Charge | 0 |
| Complexity | 3240 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 15 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.