504-24-5
Product Name:
4-Aminopyridine
Formula:
C5H6N2
Synonyms:
4-Aminopyridine;4AP;4-Pyridinamine;4-Pyridylamine;Fampridine
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | White crystals; [CAMEO] Formulated as grain bait or powder concentrate; [EXTOXNET] |
|---|---|
| Color/Form | White crystals |
| Odor | Odorless |
| Boiling Point | 273°C |
| Melting Point | 157-161°C |
| Solubility | 74 g/L |
| Density | 1.2607 |
| Vapor Pressure | 0.00034 [mmHg] |
| LogP | log Kow = 0.32 |
| Stability/Shelf Life | Stable under recommended storage conditions. |
| Decomposition | When heated to decomposition it emits toxic fumes of /nitrogen oxides/. |
| Ionization Efficiency | Positive |
| Dissociation Constants | 11 |
| Collision Cross Section | 117.8 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
| Kovats Retention Index | 1170 |
| Other Experimental Properties | Stable to light |
| Chemical Classes | Pesticides -> Avicides |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06  Environment GHS09 |
| GHS Hazard Statements |
H300:Acute toxicity,oral H314:Skin corrosion/irritation H411:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
| Molecular Weight | 94.11 g/mol |
|---|---|
| XLogP3 | 0.3 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 0 |
| Exact Mass | 94.053098200 g/mol |
| Monoisotopic Mass | 94.053098200 g/mol |
| Topological Polar Surface Area | 38.9 Ų |
| Heavy Atom Count | 7 |
| Formal Charge | 0 |
| Complexity | 48 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
4-aminopyridine is an aromatic amine that is pyridine bearing a single amino substituent at position 4. An orphan drug in the US, it is used to improve walking in adults with multiple sclerosis. It has a role as an avicide, a potassium channel blocker and an orphan drug. It is an aromatic amine and an aminopyridine.