CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Melting Point | 169-171 °C (Protriptyline HCl) |
| Solubility | 1.04 mg/L |
| LogP | 4.7 |
| Stability/Shelf Life | REASONABLY STABLE IN LIGHT, STABLE IN AIR, & STABLE IN HEAT UNDER USUAL PREVAILING TEMP /HYDROCHLORIDE/ |
| Decomposition | When heated to decomposition it emits toxic fumes of nitroxides. |
| Collision Cross Section | 162.8 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)] |
| Kovats Retention Index | 2251 2226 2226 2207 2230 2254 2246 2261 2238 2237 2265 2232.1 |
| Other Experimental Properties | ODORLESS OR HAS NOT MORE THAN SLIGHT ODOR & HAS BITTER TASTE; WHITE TO YELLOWISH POWDER /HYDROCHLORIDE/ |
COMPUTED DESCRIPTORS
| Molecular Weight | 263.4 g/mol |
|---|---|
| XLogP3 | 4.4 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 4 |
| Exact Mass | 263.167399674 g/mol |
| Monoisotopic Mass | 263.167399674 g/mol |
| Topological Polar Surface Area | 12 Ų |
| Heavy Atom Count | 20 |
| Formal Charge | 0 |
| Complexity | 296 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Protriptyline is a carbotricyclic compound. It has a role as an antidepressant. It derives from a hydride of a dibenzo[a,d][7]annulene.