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405940-76-3

405940-76-3 structural image
Product Name: Razaxaban (Hydrochloride)
Formula: C24H21ClF4N8O2
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COMPUTED DESCRIPTORS

Molecular Weight 564.9 g/mol
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 11
Rotatable Bond Count 6
Exact Mass 564.1412123 g/mol
Monoisotopic Mass 564.1412123 g/mol
Topological Polar Surface Area 120 Ų
Heavy Atom Count 39
Formal Charge 0
Complexity 838
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Razaxaban Hydrochloride is the hydrochloride salt form of razaxaban, an orally active, 1,2-benzisoxazole-containing, inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Razaxaban forms an isoxazole-ring opened, stable, benzamidine metabolite which is subsequently excreted through the bile.