318-98-9
Product Name:
Propranolol hydrochloride
Formula:
C16H22ClNO2
Synonyms:
(±)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride;(±)-Propranolol hydrochloride;DL -Propranolol hydrochloride
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | White or almost white powder |
|---|---|
| Odor | Odorless |
| Taste | Bitter |
| Melting Point | 163-164 °C |
| Solubility | >44.4 [ug/mL] (The mean of the results at pH 7.4) |
| LogP | log Kow = -0.45 @ pH 2.0 |
| Stability/Shelf Life | IT IS STABLE TO HEAT, UNSTABLE TO LIGHT. /HYDROCHLORIDE/ |
| Decomposition | When heated to decomposition it emits toxic fumes of oxides of nitrogen. |
| Dissociation Constants | pKa = 9.45 |
| Other Experimental Properties | Intense mass spectral peaks: 72 m/z, 100 m/z, 144 m/z, 259 m/z /Propranolol/ |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
COMPUTED DESCRIPTORS
| Molecular Weight | 295.80 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 6 |
| Exact Mass | 295.1339066 g/mol |
| Monoisotopic Mass | 295.1339066 g/mol |
| Topological Polar Surface Area | 41.5 Ų |
| Heavy Atom Count | 20 |
| Formal Charge | 0 |
| Complexity | 257 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Propranolol Hydrochloride is the hydrochloride form of propranolol, a synthetic beta-adrenergic receptor blocker with antianginal, antiarrhythmic, and antihypertensive properties. Propranolol competitively antagonizes beta-adrenergic receptors, thereby inhibiting beta-adrenergic reactions, such as vasodilation, and negative chronotropic and inotropic effects.
RELATED SUPPLIERS
Padmavati Pharmachem
Mumbai
product:Powder Propranolol Hydrochloride IP, Grade Standard: Medicine Grade, 3506-09-0