CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Boiling Point | 421.5 ºC at 760 mm Hg |
| Melting Point | 221-223 |
| Solubility | Soluble |
| LogP | 5.37 |
| Dissociation Constants | 9.43 |
COMPUTED DESCRIPTORS
| Molecular Weight | 259.13 g/mol |
|---|---|
| XLogP3 | 2.6 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 3 |
| Exact Mass | 258.0326684 g/mol |
| Monoisotopic Mass | 258.0326684 g/mol |
| Topological Polar Surface Area | 33.6 Ų |
| Heavy Atom Count | 16 |
| Formal Charge | 0 |
| Complexity | 263 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Lofexidine is a member of imidazoles, a dichlorobenzene, an aromatic ether and a carboxamidine. It has a role as an alpha-adrenergic agonist and an antihypertensive agent.