3056-17-5
Product Name:
Stavudine
Formula:
C10H12N2O4
Synonyms:
Stavudine;d4T;1-(2,3-Dideoxy-β-D -glycero-pent-2-enofuranosyl)thymine;1-[(2R,5S)-5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-(1H,3H)-dione;2′,3′-Anhydrothymidine
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | 2',3'-didehydro-3'-deoxythymidine appears as white crystalline solid or powder. Odorless. (NTP, 1992) |
|---|---|
| Color/Form | White to off white crystalline solid |
| Melting Point | 318 to 320 °F (NTP, 1992) |
| Solubility | 50 to 100 mg/mL at 70 °F (NTP, 1992) |
| Vapor Pressure | 9.5X10-12 mm Hg at 25 °C /Estimated/ |
| LogP | -0.72 |
| Henry's Law Constant | Henry's Law constant = 2.3X10-15 atm-cu m/mole at 25 °C /Estimated/ |
| Other Experimental Properties | Hydroxyl radical reaction rate constant = 1.21X10-10 cu cm/molec-sec at 25 °C /Estimated/ |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H341:Germ cell mutagenicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P501:Dispose of contents/container to..… |
COMPUTED DESCRIPTORS
| Molecular Weight | 224.21 g/mol |
|---|---|
| XLogP3 | -0.8 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 2 |
| Exact Mass | 224.07970687 g/mol |
| Monoisotopic Mass | 224.07970687 g/mol |
| Topological Polar Surface Area | 78.9 Ų |
| Heavy Atom Count | 16 |
| Formal Charge | 0 |
| Complexity | 388 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
2',3'-didehydro-3'-deoxythymidine appears as white crystalline solid or powder. Odorless. (NTP, 1992)