CHEMICAL AND PHYSICAL PROPERTIES
| Melting Point | 198 °C |
|---|---|
| Solubility | Readily soluble in ethyl acetate and chloroform; less soluble in water, ethanol, acetone and benzene |
| Vapor Pressure | 3X10-14 mm Hg @ 25 °C /Estimated/ |
| LogP | log Kow = -0.27 @ 25 °C /Estimated/ |
| Henry's Law Constant | Henry's Law constant = 1.6X10-13 atm-cu m/mol @ 25 °C /Estimated/ |
| Stability/Shelf Life | Stable at room temp in closed containers. |
| Optical Rotation | Specific optical rotation: -6.2 deg @ 15 dec C/D (in chloroform); max absorption: 215 nm (epsilon= 286) |
| Decomposition | When heated to decomposition it emits toxic fumes of /nitrogen oxide/. |
| Other Experimental Properties | Readily hydrolyzed with alkali |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
COMPUTED DESCRIPTORS
| Molecular Weight | 365.4 g/mol |
|---|---|
| XLogP3 | 1.4 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 0 |
| Exact Mass | 365.18383758 g/mol |
| Monoisotopic Mass | 365.18383758 g/mol |
| Topological Polar Surface Area | 93.1 Ų |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 652 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 2 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Senkirkine is a macrolide.