22601-59-8
Product Name:
Bacitracin F, 1-[N-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl]carbonyl]-l-leucine]-
Formula:
C66H103N17O16S
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Melting Point | 221 - 225 °C |
| Solubility | Freely soluble |
| LogP | -0.8 |
COMPUTED DESCRIPTORS
| Molecular Weight | 1422.7 g/mol |
|---|---|
| XLogP3 | -4.1 |
| Hydrogen Bond Donor Count | 17 |
| Hydrogen Bond Acceptor Count | 21 |
| Rotatable Bond Count | 31 |
| Exact Mass | 1421.74894144 g/mol |
| Monoisotopic Mass | 1421.74894144 g/mol |
| Topological Polar Surface Area | 556 Ų |
| Heavy Atom Count | 100 |
| Formal Charge | 0 |
| Complexity | 2850 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 15 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Bacitracin A is a homodetic cyclic peptide consisting of (4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carboxylic acid attached head-to-tail to L-leucyl,D-glutamyl, L-lysyl, D-ornityl, L-isoleucyl, D-phenylalanyl, L-histidyl. D-aspartyl and L-asparaginyl residues coupled in sequence and cyclised by condensation of the side-chain amino group of the L-lysyl residue with the C-terminal carboxylic acid group. It is the major component of bacitracin. It has a role as an antibacterial agent and an antimicrobial agent. It is a homodetic cyclic peptide and a polypeptide.