217082-58-1
Product Name:
GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE
Formula:
C69H111N23O16S
Synonyms:
Prepro-65-77-Apelin
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COMPUTED DESCRIPTORS
| Molecular Weight | 1550.8 g/mol |
|---|---|
| XLogP3 | -7.1 |
| Hydrogen Bond Donor Count | 19 |
| Hydrogen Bond Acceptor Count | 22 |
| Rotatable Bond Count | 47 |
| Exact Mass | 1549.82998572 g/mol |
| Monoisotopic Mass | 1549.82998572 g/mol |
| Topological Polar Surface Area | 658 Ų |
| Heavy Atom Count | 109 |
| Formal Charge | 0 |
| Complexity | 3140 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 12 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Apelin-13 is a 13 amino acid oligopeptide which is the ligand for the apelin receptor (also known as the APJ receptor). It exhibits hypotensive and neuroprotective effects, and may be a potential prognostic biomarker for acute ischemic stroke and multiple sclerosis. It has a role as an antihypertensive agent, a biomarker, an autophagy inhibitor, a neuroprotective agent and a human metabolite. It is a conjugate base of an apelin-13(3+).