CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | White to off-white solid |
|---|---|
| Solubility | In water, 77,000 mg/l @ 25 °C |
| Vapor Pressure | VP: 3.1X10-13 mm Hg @ 25 °C /Estimated/ /Abacavir/ |
| LogP | log Kow = 1.2 @ 25 °C |
| Henry's Law Constant | Henry's Law constant = 1.9X10-16 atm-cu m/mol @ 25 °C /Estimated/ /Abacavir/ |
| Other Experimental Properties | UV max: 296, 255 (epsilon=14000, 10700), pH = 1; 284, 259 (epsilon=15900, 9200) pH = 7 /Abacavir/ |
COMPUTED DESCRIPTORS
| Molecular Weight | 384.41 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 10 |
| Rotatable Bond Count | 4 |
| Exact Mass | 384.12158893 g/mol |
| Monoisotopic Mass | 384.12158893 g/mol |
| Topological Polar Surface Area | 185 Ų |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 496 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Abacavir (brand name: Ziagen) is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults, children, and infants. Abacavir is always used in combination with other HIV medicines.