COMPUTED DESCRIPTORS
| Molecular Weight | 1304.5 g/mol |
|---|---|
| XLogP3 | -2 |
| Hydrogen Bond Donor Count | 9 |
| Hydrogen Bond Acceptor Count | 27 |
| Rotatable Bond Count | 52 |
| Exact Mass | 1303.72484521 g/mol |
| Monoisotopic Mass | 1303.72484521 g/mol |
| Topological Polar Surface Area | 383 Ų |
| Heavy Atom Count | 90 |
| Formal Charge | 0 |
| Complexity | 1870 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 15 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Uproleselan is a novel, specific E-Selectin antagonist under investigation in clinical trial NCT02306291 (Study to Determine Safety, Pharmacokinetics and Efficacy of GMI-1271 in Combination With Chemotherapy in AML).