COMPUTED DESCRIPTORS
| Molecular Weight | 1117.1 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 10 |
| Hydrogen Bond Acceptor Count | 25 |
| Rotatable Bond Count | 16 |
| Exact Mass | 1116.42384683 g/mol |
| Monoisotopic Mass | 1116.42384683 g/mol |
| Topological Polar Surface Area | 364 Ų |
| Heavy Atom Count | 79 |
| Formal Charge | 0 |
| Complexity | 1850 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 13 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 3 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Vinflunine Ditartrate is the ditartrate salt of vinflunine, a bi-fluorinated derivative of the semisynthetic vinca alkaloid vinorelbine with potential antimitotic and antineoplastic activities. Vinflunine binds to tubulin and inhibits tubulin assembly and disrupts microtubule assembly dynamics. This results in cell cycle arrest in mitosis and an induction of apoptosis.