175178-82-2
Product Name:
AG 1478
Formula:
C16H14ClN3O2
Synonyms:
4-(3-Chloroanilino)-6,7-dimethoxyquinazoline;AG 1478 - CAS 175178-82-2 - Calbiochem;InSolution AG 1478 - CAS 175178-82-2 - Calbiochem;N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinamine
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COMPUTED DESCRIPTORS
| Molecular Weight | 315.75 g/mol |
|---|---|
| XLogP3 | 4 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 4 |
| Exact Mass | 315.0774544 g/mol |
| Monoisotopic Mass | 315.0774544 g/mol |
| Topological Polar Surface Area | 56.3 Ų |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 360 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Tyrphostin AG 1478 is a member of the class of quinazolines that is quinazoline substituted by methoxy groups at positions 6 and 7 and a (3-chlorophenyl)nitrilo group at position 4. It acts as an epidermal growth factor receptor antagonist. It has a role as an epidermal growth factor receptor antagonist, an antineoplastic agent, a geroprotector and an antiviral agent. It is a member of quinazolines, an aromatic ether and a member of monochlorobenzenes.