163955-22-4
Product Name:
Hydrazinecarboximidamide, 2,2'-(1-methyl-1,2-ethanediylidene)bis-, (E,E)- (9CI)
Formula:
C5H12N8
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Solubility | 0.1 N NaOH soluble (mg/mL) |
|---|---|
| Stability/Shelf Life | Solution: A solution of 100 mg/mL in water stored at room temperature for 44 days showed no decomposition. |
COMPUTED DESCRIPTORS
| Molecular Weight | 184.20 g/mol |
|---|---|
| XLogP3 | -2.2 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 184.11849242 g/mol |
| Monoisotopic Mass | 184.11849242 g/mol |
| Topological Polar Surface Area | 154 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 264 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 2 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Mitoguazone is a hydrazone obtained by formal condensation of the two carbonyl groups of methylglyoxal with the primary amino groups of two molecules of aminoguanidine. It has a role as an antineoplastic agent, an apoptosis inducer and an EC 4.1.1.50 (adenosylmethionine decarboxylase) inhibitor. It is a hydrazone and a member of guanidines. It is functionally related to a methylglyoxal and an aminoguanidine. It is a conjugate base of a mitoguazone(2+).