14930-96-2
Product Name:
CYTOCHALASIN B
Formula:
C29H37NO5
Synonyms:
Cytochalasin B, Helminthosporium dematioideum - CAS 14930-96-2 - Calbiochem;Phomin
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid; [Merck Index] White crystalline solid; [MSDSonline] |
|---|---|
| Color/Form | FELTED NEEDLES FROM ACETONE |
| Melting Point | 218-221 °C |
| Optical Rotation | SPECIFIC OPTICAL ROTATION: +86.7 DEG @ 21 °C/D (C= 0.9 IN METHANOL), +84 DEG @ 25 °C/D (C= 1.0 IN ETHANOL); MP: 218 °C, FROM CHLOROFORM SOLUTION; MAX ABSORPTION: 229 NM (E= 44,668), 257 NM (SHOULDER), 265 NM (SHOULDER), 269 NM (SHOULDER) |
| Chemical Classes | Biological Agents -> Mycotoxins |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H361:Reproductive toxicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
COMPUTED DESCRIPTORS
| Molecular Weight | 479.6 g/mol |
|---|---|
| XLogP3 | 3.4 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 2 |
| Exact Mass | 479.26717328 g/mol |
| Monoisotopic Mass | 479.26717328 g/mol |
| Topological Polar Surface Area | 95.9 Ų |
| Heavy Atom Count | 35 |
| Formal Charge | 0 |
| Complexity | 859 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 8 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 2 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Cytochalasin B is an organic heterotricyclic compound, that is a mycotoxin which is cell permeable an an inhibitor of cytoplasmic division by blocking the formation of contractile microfilaments. It has a role as a metabolite, a platelet aggregation inhibitor, a mycotoxin and an actin polymerisation inhibitor. It is a cytochalasin, an organic heterotricyclic compound, a lactam and a lactone.