132-98-9
Product Name:
Penicillin V potassium salt
Formula:
C16H17KN2O5S
Synonyms:
Penicillin V potassium salt;Phenoxymethylpenicillin potassium salt
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Penicillin vk+ is an odorless white crystalline powder. Slightly bitter taste. pH (0.5% aqueous solution) 5 to 7.5. (NTP, 1992) |
|---|---|
| Color/Form | White, colorless crystalline powder |
| Odor | Odorless |
| Melting Point | 387 to 396 °F (NTP, 1992) |
| Solubility | greater than or equal to 100 mg/mL at 72 °F (NTP, 1992) |
| Density | 1.4 (NTP, 1992) - Denser than water; will sink |
| Optical Rotation | Specific optical rotation: +223 deg at 25 °C/D (c= 0.2) |
| pH | 5-7.5 in solution |
| Dissociation Constants | pKa= 2.73 |
| Collision Cross Section | 182.7 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
| Other Experimental Properties | White, odorless, crystalline powder; very slightly soluble in water; soluble in alcohol and acetone; insoluble in fixed oils, pH of saturated solution is 2.5-4.0, decomposes at 120 °C /penicillin V/ |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H317:Sensitisation, Skin H334:Sensitisation, respiratory |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
COMPUTED DESCRIPTORS
| Molecular Weight | 388.5 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 5 |
| Exact Mass | 388.04952431 g/mol |
| Monoisotopic Mass | 388.04952431 g/mol |
| Topological Polar Surface Area | 124 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 553 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Penicillin vk+ is an odorless white crystalline powder. Slightly bitter taste. pH (0.5% aqueous solution) 5 to 7.5. (NTP, 1992)