CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid; [Merck Index] White hygroscopic crystals; [Alfa Aesar MSDS] |
|---|---|
| Color/Form | Crystalline mass |
| Odor | SLIGHT, CHARACTERISTIC ODOR |
| Taste | FAINT, SWEET, SOAPY TASTE |
| Boiling Point | 219-220 °C at 10 mm Hg |
| Melting Point | 171-172 °C |
| Solubility | 79.1 mg/mL in ethylene glycol; 26 mg/mL in methanol; 14.6 mg/mL in anhyd ethanol; 22 mg/mL in 95% ethanol; 14 mg/mL in dimethyl formamide; 20 mg/mL in acetone; 0.5 mg/mL in ethyl acetate; 0.4 mg/mL in olive oil; 0.1 mg/mL in cyclohexane; 0.05 mg/mL in chloroform; less than 0.05 mg/mL in carbon tetrachloride |
| Vapor Pressure | 0.000022 [mmHg] |
| Stability/Shelf Life | Stable in light and air |
| Decomposition | When heated to decomposition it emits toxic fumes of /nitrogen oxide/. |
| pH | pH of 0.1 molar aq soln = 10.4 |
| Dissociation Constants | 8.08 |
| Kovats Retention Index | 1645 |
| Other Experimental Properties | Weak, monoacidic base; aq soln do not absorb CO2 from air |
| Chemical Classes | Other Uses -> Biological Buffers |
COMPUTED DESCRIPTORS
| Molecular Weight | 121.14 g/mol |
|---|---|
| XLogP3 | -2.9 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 121.07389321 g/mol |
| Monoisotopic Mass | 121.07389321 g/mol |
| Topological Polar Surface Area | 86.7 Ų |
| Heavy Atom Count | 8 |
| Formal Charge | 0 |
| Complexity | 54 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Tris is a primary amino compound that is tert-butylamine in which one hydrogen attached to each methyl group is replaced by a hydroxy group. A compound widely used as a biological buffer substance in the pH range 7--9; pKa = 8.3 at 20 ℃; pKa = 7.82 at 37 ℃. It has a role as a buffer. It is a triol and a primary amino compound. It is a conjugate base of a member of Htris.