122879-69-0
Product Name:
H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
Formula:
C115H160N26O32S4
Synonyms:
ET-2
Inquiry
COMPUTED DESCRIPTORS
| Molecular Weight | 2546.9 g/mol |
|---|---|
| XLogP3 | -2.6 |
| Hydrogen Bond Donor Count | 33 |
| Hydrogen Bond Acceptor Count | 39 |
| Rotatable Bond Count | 46 |
| Exact Mass | 2546.0608366 g/mol |
| Monoisotopic Mass | 2545.0574817 g/mol |
| Topological Polar Surface Area | 1030 Ų |
| Heavy Atom Count | 177 |
| Formal Charge | 0 |
| Complexity | 5550 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 23 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
A 21-amino acid peptide produced predominantly within the kidney and intestine, with smaller amounts produced in the myocardium, placenta, and uterus, but the cells of origin are not clear. Endothelin-2 has no unique physiologic functions, as compared with endothelin-1. (N Eng J Med 1995;333(6):356-63)