COMPUTED DESCRIPTORS
| Molecular Weight | 4784 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 67 |
| Hydrogen Bond Acceptor Count | 76 |
| Rotatable Bond Count | 161 |
| Exact Mass | 4783.4853177 g/mol |
| Monoisotopic Mass | 4781.4786080 g/mol |
| Topological Polar Surface Area | 2050 Ų |
| Heavy Atom Count | 335 |
| Formal Charge | 0 |
| Complexity | 11600 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 45 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Corticorelin Ovine Triflutate is a trifluoroacetate salt of ovine corticotropin-releasing hormone (CRH), a 41 amino acids peptide similar to human CRH, used as a diagnostic agent. Corticorelin ovine triflutate is a potent stimulator of adrenocorticotropic hormone (ACTH), secreted from the anterior pituitary gland. In turn, ACTH stimulates cortisol production from the adrenal cortex and is regulated by a negative feedback mechanism. Corticorelin ovine triflutate is used as a diagnostic tool in differentiating pituitary and ectopic production of ACTH.