COMPUTED DESCRIPTORS
| Molecular Weight | 299.32 g/mol |
|---|---|
| XLogP3 | 3.9 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 2 |
| Exact Mass | 299.050644 g/mol |
| Monoisotopic Mass | 299.050644 g/mol |
| Topological Polar Surface Area | 80.6 Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 390 |
| Isotope Atom Count | 1 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Fluorine F 18 W372 is a radiotracer composed of W372 radiolabeled with the radioisotope fluorine F 18, with potential amyloid-beta (Abeta) peptide imaging activity upon positron emission topography (PET). Upon administration, the W372 moiety of fluorine F 18 W372 selectively targets and binds to amyloid-beta in the brain. Upon binding, amyloid-beta plaques can be visualized and detected during PET imaging. Amyloid-beta accumulates in the brain and is a key component in plaque formation in Alzheimer's disease.