COMPUTED DESCRIPTORS
| Molecular Weight | 1427.5 g/mol |
|---|---|
| XLogP3 | -10.3 |
| Hydrogen Bond Donor Count | 22 |
| Hydrogen Bond Acceptor Count | 32 |
| Rotatable Bond Count | 37 |
| Exact Mass | 1426.57178218 g/mol |
| Monoisotopic Mass | 1426.57178218 g/mol |
| Topological Polar Surface Area | 745 Ų |
| Heavy Atom Count | 98 |
| Formal Charge | 0 |
| Complexity | 2750 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 20 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Phleomycin D1 is a glycopeptide originally isolated from the bacterium Streptomyces verticillus which contains a (4'R)-4',5'-dihydro-2,4'-bi-1,3-thiazole-2',4-diyl moiety with a a 4-guanidylbutylaminocarbonyl group attached to the 4-position of the terminal thiazole ring. Like all phleomycins, phleomycin D1 can form complexes with redox-active metals such as Co, Cu, and Fe. It has a role as an antineoplastic agent, an antifungal agent, an antimicrobial agent, an antibacterial agent and a bacterial metabolite. It is a chelate-forming peptide, a member of guanidines, a disaccharide derivative, a bi-1,3-thiazole and a glycopeptide.