COMPUTED DESCRIPTORS
| Molecular Weight | 323.39 g/mol |
|---|---|
| XLogP3 | 1 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 9 |
| Exact Mass | 323.19573968 g/mol |
| Monoisotopic Mass | 323.19573968 g/mol |
| Topological Polar Surface Area | 97.3 Ų |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 333 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Rociclovir is a purine nucleoside prodrug with activity against herpes simplex virus 1. In vivo, Rociclovir is converted to ganciclovir, which is further modified to its triphosphate form and inhibits viral DNA replication by competitive inhibition of viral DNA polymerases and incorporation into viral DNA, resulting in eventual termination of viral DNA elongation.