108050-54-0
Product Name:
Tilmicosin
Formula:
C46H80N2O13
Synonyms:
20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| LogP | log kow = 3.80 |
|---|---|
| Optical Rotation | Specific optical rotation = +12.75 °For D (sodium) line at 23 °C (c = 0.010004 in CHCl3, 5 cm) |
| Dissociation Constants | pKa = 8.18 (tertiary amine) |
| Collision Cross Section | 310.2 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
COMPUTED DESCRIPTORS
| Molecular Weight | 869.1 g/mol |
|---|---|
| XLogP3 | 3.6 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 15 |
| Rotatable Bond Count | 12 |
| Exact Mass | 868.56604061 g/mol |
| Monoisotopic Mass | 868.56604061 g/mol |
| Topological Polar Surface Area | 186 Ų |
| Heavy Atom Count | 61 |
| Formal Charge | 0 |
| Complexity | 1420 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 19 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 2 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Tilmicosin is a macrolide antibiotic with formula C46H80N2O13. It is used for the treatment of respiratory disease in cattle at high risk of developing bovine respiratory disease associated with Mannheimia haemolytica. It has a role as a cardiotoxic agent, an antibacterial drug and a calcium channel blocker. It is a macrolide antibiotic, a monosaccharide derivative and an enone.